Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep186 | Calcium and Bone | ECE2022

Bone tissue metabolism in children with dystrophic form of congenital epidermolysis bullosa before and during therapy with cholecalciferol.

Pronina Irina , Makarova Svetlana , Murashkin Nikolay , Semikina Elena , Chumbadze Tamara

Introduction: Malnutrition, deficiency of micro- and macronutrients, including calcium and vitamin D are typical for children with dystrophic form of congenital epidermolysis bullosa (DEB). Thereby, there is a slowdown in osteogenesis and in stimulation of osteoclast activity, bone tissue resorption, which leads to increased bone fragility and low-traumatic fractures.Aim of the study: To evaluate markers of bone tissue metabolism and phosphorus-calcium m...